{
  "$schema": "http://json-schema.org/draft-04/schema#",
  "$id": "https://schema.humancellatlas.org/type/protocol/biomaterial_collection/1.1.0/enrichment_protocol",
  "description": "protocol by which one biomaterial was produced from another biomaterial to favor a feature or characteristic of interest.",
  "additionalProperties": false,
  "required": [
    "describedBy",
    "schema_type",
    "protocol_core",
    "enrichment_method"
  ],
  "title": "enrichment_protocol",
  "type": "object",
  "properties": {
    "describedBy": {
      "description": "The URL reference to the schema.",
      "type": "string",
      "pattern": "https://schema.humancellatlas.org/type/protocol/biomaterial_collection/[0-9]{1,}.[0-9]{1,}.[0-9]{1,}/enrichment_protocol"
    },
    "schema_version": {
      "description": "The version number of the schema in major.minor.patch format.",
      "type": "string",
      "pattern": "^[0-9]{1,}.[0-9]{1,}.[0-9]{1,}$",
      "example": "4.6.1"
    },
    "schema_type": {
      "description": "The type of the metadata schema entity.",
      "type": "string",
      "enum": [
        "protocol"
      ]
    },
    "protocol_core": {
      "description": "Core protocol-level information.",
      "type": "object",
      "$ref": "https://schema.humancellatlas.org/core/protocol/5.1.0/protocol_core"
    },
    "enrichment_method": {
      "description": "The method by which enrichment was achieved. Should be a child term of EFO - enrichment process",
      "type": "object",
      "$ref": "https://schema.humancellatlas.org/module/ontology/1.0.0/enrichment_ontology",
      "user_friendly": "Enrichment method"
    },
    "markers": {
      "description": "A space-delimited list of markers with +/-.",
      "type": "string",
      "example": "CD4+ CD8-",
      "user_friendly": "Markers"
    },
    "min_size_selected": {
      "description": "Minimum cell or organelle size passing selection, in microns.",
      "type": "number",
      "maximum": 10000,
      "minimum": 0.01,
      "user_friendly": "Minimum size selected"
    },
    "max_size_selected": {
      "description": "Maximum cell or organelle size passing selection, in microns.",
      "type": "number",
      "maximum": 10000,
      "minimum": 0.01,
      "user_friendly": "Maximum size selected"
    },
    "protocol_type": {
      "description": "The type of protocol. Should be a child term of https://www.ebi.ac.uk/ols/ontologies/efo/terms?iri=http%3A%2F%2Fwww.ebi.ac.uk%2Fefo%2FEFO_0002694.",
      "type": "object",
      "$ref": "https://schema.humancellatlas.org/module/ontology/5.1.0/process_type_ontology",
      "user_friendly": "protocol type"
    }
  }
}