{
  "$schema": "http://json-schema.org/draft-07/schema#",
  "$id": "https://schema.humancellatlas.org/type/protocol/biomaterial_collection/2.1.0/aggregate_generation_protocol",
  "description": "Information about how cultured cells are developed into cell aggregates.",
  "additionalProperties": false,
  "required": [
    "describedBy",
    "schema_type",
    "protocol_core",
    "formation_method"
  ],
  "title": "Aggregate generation protocol",
  "name": "aggregate_generation_protocol",
  "type": "object",
  "properties": {
    "describedBy": {
      "description": "The URL reference to the schema.",
      "type": "string",
      "pattern": "^(http|https)://schema.(.*?)humancellatlas.org/type/protocol/biomaterial_collection/(([0-9]{1,}.[0-9]{1,}.[0-9]{1,})|([a-zA-Z]*?))/aggregate_generation_protocol"
    },
    "schema_version": {
      "description": "The version number of the schema in major.minor.patch format.",
      "type": "string",
      "pattern": "^[0-9]{1,}.[0-9]{1,}.[0-9]{1,}$",
      "example": "4.6.1"
    },
    "schema_type": {
      "description": "The type of the metadata schema entity.",
      "type": "string",
      "enum": [
        "protocol"
      ]
    },
    "provenance": {
      "description": "Provenance information provided by the system.",
      "type": "object",
      "$ref": "https://schema.humancellatlas.org/system/1.1.0/provenance"
    },
    "protocol_core": {
      "description": "Core protocol-level information.",
      "type": "object",
      "$ref": "https://schema.humancellatlas.org/core/protocol/5.2.5/protocol_core",
      "user_friendly": "Protocol core"
    },
    "formation_method": {
      "description": "Method used to form cell aggregates.",
      "type": "string",
      "example": "rocking; suspension cultures; hanging drops; spinner flasks",
      "user_friendly": "Aggregate formation method"
    },
    "cell_uniformity": {
      "description": "Description of the cell aggregates uniformity after formation.",
      "type": "string",
      "example": "Mostly homogenous embryoid bodies of variable cell numbers; Low-homogeneity in morphology and size",
      "user_friendly": "Aggregate cell uniformity"
    }
  }
}